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4.17.2011

GIVE LOVE...

There are very few gifts of love that compare to friendship. Today, I am still on a high from the undeserved love from my dear friends and husband I felt in a huge way yesterday. Annually, Rockford First (Kelly's church) holds a woman's conference, Original, and at the end of the conference, they do a session called Original Gives. It is a time to celebrate nominated women who have made a difference in other people's lives. Kelly, my dear friend, asked Justin, Katie, Angie, and Andrea, to help her in nominating me and I was one of the recipients. All I knew was they were taking me Friday evening out to Kelly's for a sleepover, and we would be doing something on Saturday. I had no idea about the award. We arrived at the church for the conference and sat through the first session about mercy ministries. I thought it was a bit weird that this is what was so secret, but I went with it, thinking we would all get pedicures after or something. To be honest, I was just enjoying my girls and the company. When the first session ended, they changed the stage decor and put out couches. They announced the session as Original Gives (like Oprah's Favorite Things) and began to announce women they chose to honor. As they read names, the gifts became bigger and bigger. I knew at that point, my girls were up to something as they exchanged giggles and looks but never expected what happened next. They introduced the next woman and showed the video (below) and there was my name and my husband on three jumbo screens. In addition to the video, we all went on stage (Joan drove in and my mom surprised me in the front row with Brooklyn) and through the tears, I was presented with some fabulous gifts of a spa weekend, gift cards, Easter baskets for the kids and $2,500! I was so humbled. Here are my friends, who have done way more for me than I have for them, and Kelly, who out of her unselfish heart, nominated me when her herself deserved the honor. All my friends and husband are more deserving than me. They are the ones I look up to and want to be like, so for me to be the one being acknowledged....I couldn't understand. I was feeling guilty and wanted to share the gift with Kelly....and low and behold, the lovely ladies at Rockford First, Jen and Lisa, were so touched by her unselfish love they gave her gifts too! I was sooooo happy for her and it is a day I will never forget. Thank you Jacob at Rockford First, for your time putting together the video---it means the world to me! Once again, Thank you is never enough! I love you guys! Thanks!

Original Gives - Boyce Interview from Rockford First on Vimeo.

4.07.2011

Pfizer-Zacharon collaboration


This is really exciting and hopeful news in the research world for us!


By Jonathan D. Rockoff Pfizer is teaming up with a biotechnology firm in an unusual early-stage drug-development deal that could be worth as much as $210 million and bolster the drug giant's new push into rare diseases. The collaboration with Zacharon Pharmaceuticals Inc., of San Diego, provides Pfizer access to technology for identifying drugs to treat genetic diseases called lysosomal storage disorders that cause mental retardation and lead to early death. Zacharon has identified molecules that have shown promise during testing in animals and test tubes. Pfizer plans to help further develop the compounds, and assist in looking for others, the companies said. The deal, which is expected to be announced Thursday, is the first by a new Pfizer division established to work on treatments for orphan and genetic diseases, said Ed Mascioli, the division's chief. "They clearly have expertise that we don't have," Dr. Mascioli said of Zacharon. Under terms of the deal, Pfizer will provide an unspecified upfront sum and drug-development funding, along with payments if development, regulatory and commercialization milestones are met. Zacharon could also receive additional royalty and sales milestones payments if any drugs go on sale. Tie-ups between Big Pharma and small biotechs aren't uncommon, but this deal is unusual in that larger drug makers have been loath to sign up at such an unproven, early stage. The number of so-called Phase I early-stage compounds that haven't found a Big Pharma patron rose to 904 in 2009, up from 233 in 2000, according to Defined Health, a biopharmaceutical industry business development and strategy firm. But drug giants are also competing to gain a foothold in the treatment of rare diseases as they seek to replace aging blockbuster drugs. The recent mapping of the human genome has identified potential targets for new drugs, Dr. Mascioli said. In addition, therapies for rare diseases can win quick regulatory approval, command high prices and require less marketing, industry experts added. The National Institutes of Health classifies a disease as rare, or orphan, if it affects less than 200,000 people in the U.S. Since 2005, about a quarter of the new drugs approved each year aim to treat orphan diseases, according to the U.S. Food and Drug Administration. The Pfizer-Zacharon collaboration will focus on five conditions resulting from a genetic defect that makes it difficult for the body's cells to dispose of waste, which then dangerously accumulates. Current treatments can relieve many symptoms, but not the neurological effects, because the therapies can't cross the blood-brain barrier, according to the companies. Zacharon's technology can identify compounds that can be made into pills with a therapeutic impact on the brain, said Chief Executive Robin Jackman. Zacharon is a closely held company whose sole institutional investor is venture-capital fund Avalon Ventures.